Understanding Lung Conditions in World Trade Center Workers
Pulmonary Diseases in WTC Workers: Symptoms, Function, and Chest CT Correlates
This work aims to better understand the different types of lung conditions affecting World Trade Center workers and volunteers, looking at their symptoms, lung function, and advanced imaging.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11072952 on NIH RePORTER |
What this research studies
We are working to understand the various long-term lung conditions experienced by World Trade Center workers and volunteers. Our goal is to identify what causes these conditions, what other health issues might be related, and how lung function changes over time for different groups of people. We are also using advanced imaging techniques, like quantitative chest CT scans, to get a clearer picture of the lung injury and how it progresses. This will help us develop more personalized treatments and better ways to monitor and prevent these diseases.
Who could benefit from this research
Good fit: This work focuses on World Trade Center workers and volunteers who have developed chronic lower airway diseases.
Not a fit: Patients without a history of World Trade Center exposure or related lung conditions would not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to a deeper understanding of lung disease in WTC workers, allowing for more targeted treatments, improved monitoring, and better prevention strategies.
How similar studies have performed: Previous studies have established valid clinical diagnoses and demonstrated diverging lung function trajectories within this cohort, and quantitative chest CT metrics have been successfully used to characterize disease processes.
Where this research is happening
New York, United States
- Icahn School of Medicine at Mount Sinai — New York, United States (Active)
Researchers
- Principal investigator: De la Hoz, Rafael E. — Icahn School of Medicine at Mount Sinai
- Study coordinator: De la Hoz, Rafael E.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.