Understanding lung cancer differences in Black Americans
Project 4 LUNG
This study is looking at the genetic differences that might explain why Black men get lung cancer more often, even when they smoke less, and aims to find better treatments that work specifically for them.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project ID | NIH-10931547 on NIH RePORTER |
What this research studies
This research investigates the genetic differences that contribute to lung cancer disparities, particularly in Black men, who have a higher risk despite lower exposure to traditional risk factors like smoking. The project aims to identify specific genetic mutations associated with lung adenocarcinoma in Black Americans and develop laboratory models that accurately reflect these genetic backgrounds. By creating these models, the research seeks to improve understanding of how lung cancer develops and how it may respond to various treatments in this population. The ultimate goal is to enhance therapeutic strategies tailored to the unique genetic profiles of Black patients with lung cancer.
Who could benefit from this research
Good fit: Ideal candidates for this research include Black men and women diagnosed with lung adenocarcinoma.
Not a fit: Patients who do not have lung cancer or those from racial/ethnic groups other than Black Americans may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatment options for Black Americans suffering from lung cancer.
How similar studies have performed: While there has been research on lung cancer disparities, this project focuses specifically on genetic differences in Black Americans, making it a novel approach.
Where this research is happening
Gainesville, United States
- University of Florida — Gainesville, United States (Active)
Researchers
- Principal investigator: Huang, Yong — University of Florida
- Study coordinator: Huang, Yong
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.