Understanding lung cancer differences in African Americans and European Americans
Official title: Explainable AI-Based Multi-Omics Analysis of Lung Cancer Health Disparity
Funded at Florida International University · NIH-11045084 · Data updated 2026-11-12
This study is looking at why African American men are more likely to develop lung cancer than European American men, and it aims to find out how genetics and other factors play a role, so we can create better, personalized treatments for everyone.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Florida International University NIH-funded |
| Lab location | 1 site (Miami, United States) |
| Project start | March 1, 2024 |
| Project end | February 28, 2026 |
| Funding year | 2025 |
| Award (this year) | $182,228 |
| NIH project number | 5R21CA290324-02 |
| Project ID | NIH-11045084 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include African American males who are at risk for or diagnosed with lung cancer.
✕Less likely to help
Patients who do not identify as African American or who have lung cancer unrelated to genetic factors may not benefit from this research.
What this research studies
This research investigates the disparities in lung cancer development between African Americans and European Americans, focusing on the influence of race and sex. It aims to identify specific genetic and epigenetic factors that contribute to higher lung cancer rates in African American males compared to their European American counterparts. By utilizing explainable artificial intelligence, the study seeks to analyze multi-omics data to uncover patient-specific alterations that traditional studies may overlook. This personalized approach could lead to more effective treatment strategies tailored to individual genetic profiles.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment of lung cancer disparities, ultimately reducing mortality rates in affected populations.
How similar studies have gone: While similar approaches have been explored, this research aims to apply a novel combination of explainable AI and multi-omics analysis specifically targeting lung cancer disparities.
Where this research is happening
-
Florida International University
Miami, United States Active
Researchers
- Principal investigator: Mondal, Ananda Mohan — Florida International University
- Study coordinator: Mondal, Ananda Mohan
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.