Understanding long-term quality of life for people with ocular hypertension
Official title: Long-Term Quality of Life in the Ocular Hypertension Treatment Study Cohort
Funded at Washington University · NIH-10837803 · Data updated 2026-11-12
This study is looking at how different treatments and other factors affect the quality of life related to vision for people with ocular hypertension over 20 years, so if you have this condition, your experiences and feedback can help us understand how it impacts daily life and how it might change if you develop glaucoma.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project start | July 1, 2023 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $198,322 |
| NIH project number | 5R21EY034188-02 |
| Project ID | NIH-10837803 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with ocular hypertension, particularly those who have been part of the Ocular Hypertension Treatment Study cohort.
✕Less likely to help
Patients with conditions unrelated to ocular hypertension or those who have not been diagnosed with this condition may not benefit from this research.
What this research studies
This research investigates how treatment and various factors affect the quality of life related to vision for individuals with ocular hypertension over a long period. By analyzing data from a cohort of participants who have been followed for 20 years, the study aims to identify changes in vision-related quality of life and the impact of developing primary open-angle glaucoma. Participants will provide insights through questionnaires that assess their visual function and quality of life, allowing researchers to understand the long-term effects of their condition and treatment. This comprehensive approach will help clarify the relationship between clinical factors and patient-reported outcomes.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of ocular hypertension, enhancing the quality of life for patients.
How similar studies have gone: Previous studies have shown that long-term follow-up and analysis of quality of life in similar cohorts can yield valuable insights, suggesting this approach is promising.
Where this research is happening
-
Washington University
Saint Louis, United States Active
Researchers
- Principal investigator: Gordon, Mae O — Washington University
- Study coordinator: Gordon, Mae O
Related research
Other NIH-funded projects on the same topics.
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This project is working to find new eye drop treatments for glaucoma by targeting a specific protein that causes pressure buildup in the eye.
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Understanding how sudden eye pressure changes affect the optic nerve in living human eyes
This NIH grant tests how acute increases in eye pressure deform the optic nerve head in living human eyes to understand how this stress might lead to vision loss.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.