Understanding Long-Term Outcomes After Lung Transplant

Long Term Follow up of the Lung Transplant Outcomes Group Cohort

NIH-funded research University of Pennsylvania · NIH-11099858

This project continues to follow patients who have received lung transplants to better understand their health over many years.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of Pennsylvania NIH-funded
Lab location1 site (Philadelphia, United States)
Project IDNIH-11099858 on NIH RePORTER

What this research studies

Lung transplantation can extend life for people with severe lung diseases, but many patients still face challenges like chronic lung allograft dysfunction (CLAD) and a shorter life expectancy. This project builds on a large, ongoing effort called the Lung Transplant Outcomes Group (LTOG), which has already gathered information from over 3000 transplant recipients. By continuing to collect clinical data and biological samples from these patients, we hope to uncover why some people do better than others after a lung transplant. Our goal is to gain crucial insights into the long-term health of lung transplant patients.

Who could benefit from this research

Good fit: This project focuses on individuals who have previously undergone lung transplantation and were part of the original Lung Transplant Outcomes Group (LTOG) cohort.

Not a fit: Patients who have not undergone a lung transplant or were not part of the initial LTOG cohort would not directly benefit from this specific follow-up project.

Why it matters

Potential benefit: If successful, this work could lead to a better understanding of long-term lung transplant outcomes, potentially guiding new strategies to improve patient health and quality of life.

How similar studies have performed: The Lung Transplant Outcomes Group (LTOG) has been a successful multi-center effort for over a decade, providing a rich resource for this continued follow-up.

Where this research is happening

Philadelphia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acute Lung InjuryAcute Pulmonary Injury
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.