Understanding long-term memory loss in Alzheimer's disease
Official title: Digital Assessment of Long-term Forgetting in Autosomal-Dominant Alzheimer's Disease
Funded at Washington University · NIH-10914241 · Data updated 2026-11-12
This study is looking at how memory loss happens in people with a specific type of Alzheimer's disease, using new digital tools to catch early signs of memory problems that regular tests might miss, so we can help improve their daily lives sooner.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $447,833 |
| NIH project number | 5R61AG083581-02 |
| Project ID | NIH-10914241 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with a genetic predisposition to autosomal-dominant Alzheimer's disease, particularly those in the early stages of cognitive decline.
✕Less likely to help
Patients without a genetic mutation for autosomal-dominant Alzheimer's disease or those in advanced stages of dementia may not benefit from this research.
What this research studies
This research investigates how memory loss occurs in individuals with autosomal-dominant Alzheimer's disease, focusing on the early signs of cognitive decline that may not be captured by traditional memory tests. By using digital assessments, the study aims to measure memory recall over extended periods, reflecting real-life situations where patients struggle to remember important information. The approach seeks to identify subtle changes in memory that can impact quality of life, allowing for earlier intervention and better therapeutic strategies.
Why it matters
Potential benefit: If successful, this research could lead to improved methods for detecting early memory decline in Alzheimer's patients, enabling timely interventions.
How similar studies have gone: Previous studies have shown promise in using extended recall periods to assess memory loss, indicating that this approach may yield valuable insights into Alzheimer's disease.
Where this research is happening
-
Washington University
Saint Louis, United States Active
Researchers
- Principal investigator: Hassenstab, Jason J — Washington University
- Study coordinator: Hassenstab, Jason J
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.