Understanding long-term lung problems after COVID-19
Official title: Uncover mechanisms underlying the development of chronic lung sequelae post COVID-19
Funded at University of Virginia · NIH-10894885 · Data updated 2026-11-12
This study is looking into why some people have ongoing breathing problems after recovering from COVID-19, and it's for anyone who had severe COVID-19 symptoms, as well as those who had mild or no symptoms, to help find better ways to treat these issues.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Virginia NIH-funded |
| Lab location | 1 site (Charlottesville, United States) |
| Project start | August 1, 2023 |
| Project end | July 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $662,044 |
| NIH project number | 5R01HL170961-02 |
| Project ID | NIH-10894885 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults who have recovered from severe COVID-19 and are experiencing ongoing respiratory symptoms.
✕Less likely to help
Patients who had mild or asymptomatic COVID-19 and are not experiencing any long-term effects may not benefit from this research.
What this research studies
This research investigates the long-term respiratory issues that some patients experience after recovering from COVID-19. It aims to identify the cellular and molecular mechanisms that lead to chronic lung conditions, such as breathlessness and fatigue. By enrolling individuals who had severe COVID-19 and comparing them to those who had mild or no symptoms, the study will utilize clinical examinations, chest CT imaging, and pulmonary function tests to gather comprehensive data. The goal is to uncover potential therapeutic targets to improve patient outcomes.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that alleviate chronic lung issues in COVID-19 survivors.
How similar studies have gone: Other research has shown promising results in understanding post-viral syndromes, making this approach both relevant and necessary.
Where this research is happening
-
University of Virginia
Charlottesville, United States Active
Researchers
- Principal investigator: Sun, Jie — University of Virginia
- Study coordinator: Sun, Jie
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.