NIH-funded research NIH-funded research

Understanding long-term effects of brain injuries in veterans

Official title: VA-DoD Long-Term Impact of Military-Relevant Brain Injury Consortium (LIMBIC): Phenotypes of Persistent Comorbidity in Post‐9/11 Era Veterans with mTBI

Funded at VA Salt Lake City Healthcare System · NIH-11213835 · Data updated 2026-11-12

This study looks at how mild traumatic brain injuries (mTBI) affect Post-9/11 veterans over time, especially in relation to other health issues like mental health problems and chronic pain, to help improve care for those who have served.

More Brain Injury research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionVA Salt Lake City Healthcare System
NIH-funded
Lab location1 site (Salt Lake City, United States)
Project startOctober 1, 2019
Project endSeptember 30, 2025
Funding year2025
NIH project number5I01RX003443-06
Project IDNIH-11213835 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are Post-9/11 veterans who have experienced mild traumatic brain injuries.

Less likely to help

Patients who have not served in the military or those without a history of brain injuries may not benefit from this research.

What this research studies

This research investigates the long-term impact of mild traumatic brain injuries (mTBI) in Post-9/11 veterans, focusing on the development of various comorbid conditions such as neurodegenerative diseases, mental health issues, and pain syndromes. By analyzing extensive data from military health systems and trauma registries, the study aims to identify different phenotypes of comorbidity associated with mTBI. The research employs advanced algorithms and deep learning methods to assess the severity of injuries and their long-term effects on veterans' health. This comprehensive approach seeks to enhance understanding of how these injuries manifest over time and inform better care strategies.

Why it matters

Potential benefit: If successful, this research could lead to improved diagnosis and treatment strategies for veterans suffering from the long-term effects of brain injuries.

How similar studies have gone: Previous research has shown promising results in understanding brain injury comorbidities, suggesting that this approach could yield valuable insights.

Where this research is happening

  • VA Salt Lake City Healthcare System
    Salt Lake City, United States
    Active

Researchers

  • Principal investigator: Pugh, Mary Jo — VA Salt Lake City Healthcare System
  • Study coordinator: Pugh, Mary Jo

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.