Understanding long-lasting immunity against coronaviruses
Discovering Durable Pan-Coronavirus Immunity
['FUNDING_P01'] · BRIGHAM AND WOMEN'S HOSPITAL · NIH-10842885
This study is looking at new vaccines that could protect us from different types of coronaviruses, including the one that causes COVID-19, by understanding how our immune system reacts to these viruses and vaccines, so we can make them even better for everyone.
Quick facts
| Phase | ['FUNDING_P01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BRIGHAM AND WOMEN'S HOSPITAL (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-10842885 on ClinicalTrials.gov |
What this research studies
This research focuses on developing next-generation vaccines that can provide broad protection against various coronaviruses, including SARS-CoV-2. It aims to understand how different human immune responses to coronavirus infections and vaccinations can influence the effectiveness of these vaccines. By studying the immune system's response, the researchers hope to identify key factors that can enhance vaccine efficacy against evolving strains and potential future coronaviruses. The approach includes analyzing immune responses and designing vaccines that target conserved viral components to prevent immune escape.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who have been vaccinated against SARS-CoV-2 or have had a previous coronavirus infection.
Not a fit: Patients who are not at risk for coronavirus infections or those who have contraindications to vaccination may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to vaccines that offer long-lasting protection against multiple strains of coronaviruses, potentially preventing future outbreaks.
How similar studies have performed: Previous research has shown promise in developing vaccines that target conserved viral components, indicating potential for success in this area.
Where this research is happening
BOSTON, UNITED STATES
- BRIGHAM AND WOMEN'S HOSPITAL — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WESEMANN, DUANE R. — BRIGHAM AND WOMEN'S HOSPITAL
- Study coordinator: WESEMANN, DUANE R.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.