Understanding long-lasting immunity against coronaviruses
Discovering Durable Pan-Coronavirus Immunity
This study is looking at how our immune system fights off coronaviruses, especially the one that causes COVID-19, to help create better vaccines that work against different versions of the virus, and it may involve patients sharing their experiences with vaccines and infections.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10328116 on NIH RePORTER |
What this research studies
This research investigates how the immune system responds to coronaviruses, particularly focusing on Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). It aims to identify the factors that contribute to effective and broad immunity against various strains of coronaviruses, which is crucial for developing next-generation vaccines. By studying the immune responses in humans and how they differ, the research seeks to inform vaccine design that can withstand genetic changes in the virus. Patients may be involved in studies that assess their immune responses to existing vaccines and infections.
Who could benefit from this research
Good fit: Ideal candidates for participation include individuals who have been vaccinated against SARS-CoV-2 or have recovered from COVID-19.
Not a fit: Patients who are not affected by coronaviruses or have no history of vaccination or infection may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of vaccines that provide long-lasting protection against multiple strains of coronaviruses.
How similar studies have performed: Previous research has shown promise in understanding immune responses to coronaviruses, indicating that this approach could yield significant insights.
Where this research is happening
Boston, United States
- Brigham and Women's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Wesemann, Duane R. — Brigham and Women's Hospital
- Study coordinator: Wesemann, Duane R.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.