Understanding local sources of harmful E. coli in children
Phylodynamics of Shiga Toxin-Producing Escherichia coli from Local Sources
This study is looking at how a type of bacteria called Shiga toxin-producing E. coli, which can make kids sick, spreads in children under 11 years old, so we can find ways to keep them safer from these infections.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project ID | NIH-11081670 on NIH RePORTER |
What this research studies
This research investigates how Shiga toxin-producing Escherichia coli (STEC) from local sources affects children under 11 years old. By analyzing the differences between locally transmitted and non-locally transmitted strains, the study aims to identify specific characteristics of the bacteria, the hosts, and the environment that contribute to local transmission. The research employs advanced genetic analysis and epidemiological methods to track and differentiate these strains, ultimately aiming to inform public health interventions that can better protect children from these infections.
Who could benefit from this research
Good fit: Ideal candidates for this research are children under the age of 11 who may have been exposed to local sources of STEC.
Not a fit: Patients who are older than 11 years or those who have not been exposed to local sources of STEC may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved public health strategies that reduce the incidence of STEC infections in children.
How similar studies have performed: Previous research has shown success in using genetic and epidemiological methods to track pathogen transmission, suggesting that this approach may yield valuable insights.
Where this research is happening
Minneapolis, United States
- University of Minnesota — Minneapolis, United States (Active)
Researchers
- Principal investigator: Tarr, Gillian — University of Minnesota
- Study coordinator: Tarr, Gillian
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.