Understanding Liver Disease Differences in WTC Responders
Racial and Ethnic Disparities in Liver Disease in the WTC General Responder Cohort
['FUNDING_U01'] · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · NIH-11074512
This project looks at how liver disease affects World Trade Center responders, especially focusing on differences among racial and ethnic groups.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-11074512 on ClinicalTrials.gov |
What this research studies
We are looking into why some World Trade Center responders, particularly people of color, might experience liver disease differently. Our team is using a special tool called the FIB-4 score, which is already part of Mount Sinai's electronic medical records, to screen for liver disease. We will also examine existing health data to understand differences in health outcomes and study stored samples to identify toxins from the WTC dust that might contribute to liver problems. This work aims to uncover how environmental exposures and healthcare policies might impact liver health in this important group.
Who could benefit from this research
Good fit: This project focuses on individuals who are part of the Mount Sinai WTC General Responder Cohort, particularly those who are people of color.
Not a fit: Patients not associated with the WTC General Responder Cohort or those without liver disease may not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could help identify gaps in healthcare coverage and environmental factors contributing to liver disease in WTC responders, potentially leading to better screening and care for those affected.
How similar studies have performed: The FIB-4 score is a well-validated tool for liver disease screening, and previous research has shown environmental toxins can cause liver injury.
Where this research is happening
NEW YORK, UNITED STATES
- ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BRANCH, ANDREA D. — ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
- Study coordinator: BRANCH, ANDREA D.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.