Understanding liver disease differences in Hispanics
Mechanisms of Advanced NAFLD Disparities in Hispanics: A Multi-level Analysis
This study is looking at why nonalcoholic fatty liver disease (NAFLD) affects people differently, especially in the Hispanic community, and it aims to understand how lifestyle and genetics play a role in the disease getting worse, so if you have NAFLD, you might be able to help us learn more by joining the research!
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Southern California NIH-funded |
| Lab location | 1 site (Los Angeles, UNITED STATES) |
| Project ID | NIH-10739809 on NIH RePORTER |
What this research studies
This research investigates the causes and mechanisms behind nonalcoholic fatty liver disease (NAFLD) and its progression to more severe conditions like cirrhosis and liver cancer, particularly focusing on the Hispanic population. A multidisciplinary team will analyze genetic, lifestyle, environmental, and immune factors that contribute to health disparities in liver disease among Hispanics compared to non-Hispanic whites. The study will enroll 2,000 patients with varying degrees of liver fibrosis and collect biological specimens and detailed health data to understand the disease's progression. Participants will be followed over time to assess changes in their condition.
Who could benefit from this research
Good fit: Ideal candidates include Hispanic individuals and non-Hispanic whites with confirmed advanced or mild hepatic fibrosis.
Not a fit: Patients without liver disease or those not residing in the Los Angeles area may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment strategies for liver disease in Hispanic patients.
How similar studies have performed: Previous research has shown success in understanding health disparities in chronic diseases, making this approach promising.
Where this research is happening
Los Angeles, UNITED STATES
- University of Southern California — Los Angeles, United States (Active)
Researchers
- Principal investigator: Setiawan, Veronica Wendy — University of Southern California
- Study coordinator: Setiawan, Veronica Wendy
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.