Understanding liver cancer risk in patients with fatty liver disease
HCC Risk Stratification in MAFLD Cirrhosis
['FUNDING_P01'] · BAYLOR COLLEGE OF MEDICINE · NIH-10874532
This study is looking at how certain health factors can increase the risk of liver cancer in people with fatty liver disease and cirrhosis, so we can find better ways to prevent cancer for these patients.
Quick facts
| Phase | ['FUNDING_P01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BAYLOR COLLEGE OF MEDICINE (nih funded) |
| Locations | 1 site (HOUSTON, UNITED STATES) |
| Trial ID | NIH-10874532 on ClinicalTrials.gov |
What this research studies
This research investigates the changing risk factors for liver cancer, particularly focusing on patients with Metabolic Associated Fatty Liver Disease (MAFLD) and cirrhosis. By analyzing data from a large cohort of cirrhosis patients, the study aims to identify metabolic risk factors that contribute to the development of hepatocellular carcinoma (HCC). The research will utilize biospecimens and patient data to create models that help in risk stratification, ultimately aiming to improve prevention strategies for HCC in this population.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with cirrhosis, particularly those with metabolic disorders such as obesity or diabetes.
Not a fit: Patients without cirrhosis or those not affected by metabolic disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better prevention strategies for liver cancer in patients with fatty liver disease.
How similar studies have performed: Previous research has shown promising results in identifying risk factors for liver cancer in similar patient populations, indicating that this approach has potential for success.
Where this research is happening
HOUSTON, UNITED STATES
- BAYLOR COLLEGE OF MEDICINE — HOUSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: EL-SERAG, HASHEM B — BAYLOR COLLEGE OF MEDICINE
- Study coordinator: EL-SERAG, HASHEM B
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.