Understanding life after sarcoma at all ages

CAUSAL: Cohort to Augment the Understanding of Sarcoma Survivorship Across the Lifespan

NIH-funded research Vanderbilt University Medical Center · NIH-11171614

This project follows sarcoma survivors of all ages to learn how treatments, biology, and lifestyle affect long-term health and quality of life.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionVanderbilt University Medical Center NIH-funded
Lab location1 site (Nashville, United States)
Project IDNIH-11171614 on NIH RePORTER

What this research studies

As a participant, you'll be invited into a long-term group of about 2,100 sarcoma survivors treated through Vanderbilt. The team will collect your treatment and medical history, repeat surveys about lifestyle and quality of life, and biospecimens such as tumor tissue and blood over time. They will track cancer recurrence, organ-related side effects, physical function, and survival while linking these outcomes to tumor biology and inherited genetics and exploring liquid biopsy tools. You may be contacted for clinic visits, blood draws, and periodic questionnaires during follow-up.

Who could benefit from this research

Good fit: People who have been diagnosed and treated for sarcoma at any age and are willing to share medical records, provide blood samples, and complete follow-up visits and questionnaires.

Not a fit: Individuals without a history of sarcoma or those unwilling to provide medical information or biospecimens would not directly benefit from participating.

Why it matters

Potential benefit: If successful, this work could help identify factors that improve survival and reduce long-term side effects for sarcoma survivors.

How similar studies have performed: Pediatric cancer survivor cohorts have produced useful insights, but a large, sarcoma-specific survivorship cohort is relatively new and less tested.

Where this research is happening

Nashville, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.