Understanding Leukemia's Genetic Changes
Core 1: Genomics
This core facility helps scientists at Memorial Sloan Kettering Cancer Center understand the genetic changes in leukemia to find better ways to fight the disease.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sloan-Kettering Inst Can Research NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11124234 on NIH RePORTER |
What this research studies
Our team focuses on uncovering the genetic, transcriptional, and epigenetic changes that cause acute myeloid leukemia (AML) to develop and resist treatment. We use advanced genomic techniques to analyze these changes, looking for new ways to target the disease. By integrating different types of genetic information, we aim to identify potential new treatments and understand why current therapies sometimes stop working. This work provides crucial support for multiple research projects dedicated to improving outcomes for patients with leukemia.
Who could benefit from this research
Good fit: Patients with acute myeloid leukemia who might benefit from future targeted therapies based on genetic insights are the ultimate focus of this research.
Not a fit: Patients whose leukemia does not involve the specific genetic or molecular pathways being studied by the supported research projects may not directly benefit from these particular findings.
Why it matters
Potential benefit: If successful, this work could lead to the discovery of new drug targets and more effective treatments for acute myeloid leukemia.
How similar studies have performed: Genomic core facilities are a standard and highly successful approach to providing essential technical and analytical support for complex cancer research projects.
Where this research is happening
New York, United States
- Sloan-Kettering Inst Can Research — New York, United States (Active)
Researchers
- Principal investigator: Papaemmanuil, Elli — Sloan-Kettering Inst Can Research
- Study coordinator: Papaemmanuil, Elli
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.