Understanding language processing in minimally verbal children with autism
Electrophysiological correlates of language processing in minimally verbal children with ASD: Elucidating pathways to language impairment
This study is looking into why some kids with autism don't talk much even after getting help, using special brain scans to understand how they process language, so we can find better ways to support their communication skills.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Children's Hospital of Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project ID | NIH-10614364 on NIH RePORTER |
What this research studies
This research investigates the reasons why some children with autism spectrum disorder (ASD) remain minimally verbal despite receiving interventions. By using electroencephalography (EEG), the study aims to measure different aspects of language processing in these children and identify biological mechanisms that may affect their language development. The research will analyze EEG data to uncover neurobiological traits that contribute to language impairment, which could help tailor interventions more effectively. The findings are expected to provide insights into the developmental trajectories of minimally verbal children with ASD.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-11 years who are diagnosed with autism spectrum disorder and are minimally verbal.
Not a fit: Patients who are not diagnosed with autism spectrum disorder or who are verbally proficient may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved interventions for minimally verbal children with autism, enhancing their language development and communication skills.
How similar studies have performed: While there has been limited research specifically focusing on minimally verbal children with ASD using EEG, similar approaches in other populations have shown promise in understanding language processing.
Where this research is happening
Los Angeles, United States
- Children's Hospital of Los Angeles — Los Angeles, United States (Active)
Researchers
- Principal investigator: Distefano, Charlotte Alcestis — Children's Hospital of Los Angeles
- Study coordinator: Distefano, Charlotte Alcestis
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.