Understanding Language and Thinking Skills in Children with DLD and Fragile X Syndrome

The relationship between language and executive function in DLD and FXS over time

['FUNDING_R01'] · UNIVERSITY OF WISCONSIN-MADISON · NIH-11085991

This project looks at how language and thinking skills develop together in children with developmental language disorder (DLD) and fragile X syndrome (FXS).

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF WISCONSIN-MADISON (nih funded)
Locations1 site (MADISON, UNITED STATES)
Trial IDNIH-11085991 on ClinicalTrials.gov

What this research studies

We are exploring how language challenges affect children with developmental language disorder (DLD) and fragile X syndrome (FXS). This includes looking closely at how they understand and use grammar, and how these language skills connect with their thinking abilities, like attention and problem-solving. By comparing these two conditions, we hope to learn more about the unique ways language and thinking develop in each. This long-term approach will help us see how these skills change over time in affected children.

Who could benefit from this research

Good fit: Children aged 0-11 years old with a diagnosis of developmental language disorder (DLD) or fragile X syndrome (FXS) may be ideal candidates for this type of research.

Not a fit: Patients without DLD or FXS, or those outside the specified age range, would likely not directly benefit from participation in this specific research.

Why it matters

Potential benefit: If successful, this work could lead to better ways to support language and thinking development in children with DLD and fragile X syndrome.

How similar studies have performed: While previous work has shown a link between executive function and language in typical development and DLD, this specific comparison and longitudinal approach in FXS is new.

Where this research is happening

MADISON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Communication Disorders

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.