Understanding Kidney Transplant Outcomes for People with African Ancestry
6/14 APOL1 Long-term Kidney Transplantation Outcomes Network (APOLLO) Clinical Center
This project helps us learn how a specific gene affects kidney transplant success and living donor kidney health for people of African ancestry.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Weill Medical Coll of Cornell Univ NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11143154 on NIH RePORTER |
What this research studies
This project is part of a national network called the APOLLO Consortium, which focuses on kidney transplant outcomes. We are looking at how certain gene variations, called APOL1 risk variants, impact the long-term health of transplanted kidneys and the kidney function of living donors. These APOL1 gene variations are more common in people of African ancestry and can increase the risk of kidney disease. Our center works with several transplant programs to follow kidney transplant recipients and living donors of African ancestry, collecting information and DNA samples to better understand these connections.
Who could benefit from this research
Good fit: Ideal candidates would be kidney transplant recipients or living kidney donors of African ancestry.
Not a fit: Patients who are not of African ancestry or are not involved in kidney transplantation may not directly benefit from this specific research.
Why it matters
Potential benefit: This work could lead to better ways to predict kidney transplant success and improve care for kidney transplant recipients and living donors of African ancestry.
How similar studies have performed: The APOLLO Consortium has been actively studying this area since 2017, building upon existing knowledge to deepen our understanding of APOL1's role.
Where this research is happening
New York, United States
- Weill Medical Coll of Cornell Univ — New York, United States (Active)
Researchers
- Principal investigator: Dadhania, Darshana — Weill Medical Coll of Cornell Univ
- Study coordinator: Dadhania, Darshana
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.