Understanding kidney injury and high blood pressure in children with HIV
Pathogenesis of renal injury and hypertension in HIV+ children
This study is looking at how HIV impacts kidney health and blood pressure in kids and teens, trying to figure out why they don’t always get high blood pressure early on, even when they have risk factors, so we can find better ways to help them stay healthy.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Virginia NIH-funded |
| Lab location | 1 site (Charlottesville, United States) |
| Project ID | NIH-11105846 on NIH RePORTER |
What this research studies
This research investigates how HIV affects kidney health and blood pressure in children and adolescents. It focuses on understanding why young individuals with HIV do not develop high blood pressure in the early stages of kidney disease, despite having risk factors. The study involves monitoring children living with HIV and analyzing the role of specific proteins and systems in their kidney function. By exploring these mechanisms, the research aims to identify potential treatments that could improve health outcomes for these patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are children and adolescents living with HIV, particularly those experiencing early stages of kidney disease.
Not a fit: Patients who are not living with HIV or who do not have kidney-related complications may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better management and treatment options for kidney disease in children with HIV.
How similar studies have performed: Previous studies have shown promising results in understanding kidney disease mechanisms in HIV, but this specific approach is novel.
Where this research is happening
Charlottesville, United States
- University of Virginia — Charlottesville, United States (Active)
Researchers
- Principal investigator: Ray, Patricio E. — University of Virginia
- Study coordinator: Ray, Patricio E.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.