Understanding kidney injury and high blood pressure in children with HIV
Official title: Pathogenesis of renal injury and hypertension in HIV+ children
Funded at University of Virginia · NIH-11105846 · Data updated 2026-11-12
This study is looking at how HIV impacts kidney health and blood pressure in kids and teens, trying to figure out why they don’t always get high blood pressure early on, even when they have risk factors, so we can find better ways to help them stay healthy.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Virginia NIH-funded |
| Lab location | 1 site (Charlottesville, United States) |
| Project start | April 15, 2023 |
| Project end | February 28, 2027 |
| Funding year | 2025 |
| Award (this year) | $664,746 |
| NIH project number | 5R01DK136417-03 |
| Project ID | NIH-11105846 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children and adolescents living with HIV, particularly those experiencing early stages of kidney disease.
✕Less likely to help
Patients who are not living with HIV or who do not have kidney-related complications may not benefit from this research.
What this research studies
This research investigates how HIV affects kidney health and blood pressure in children and adolescents. It focuses on understanding why young individuals with HIV do not develop high blood pressure in the early stages of kidney disease, despite having risk factors. The study involves monitoring children living with HIV and analyzing the role of specific proteins and systems in their kidney function. By exploring these mechanisms, the research aims to identify potential treatments that could improve health outcomes for these patients.
Why it matters
Potential benefit: If successful, this research could lead to better management and treatment options for kidney disease in children with HIV.
How similar studies have gone: Previous studies have shown promising results in understanding kidney disease mechanisms in HIV, but this specific approach is novel.
Where this research is happening
-
University of Virginia
Charlottesville, United States Active
Researchers
- Principal investigator: Ray, Patricio E. — University of Virginia
- Study coordinator: Ray, Patricio E.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.