Understanding kidney function changes during blood pressure treatments in chronic kidney disease.
Acute declines in kidney function during blood pressure interventions in CKD
This study is looking at how lowering blood pressure and using certain medications can impact kidney function in people with chronic kidney disease, to help find safe ways to manage their treatment and keep them healthy.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-10596479 on NIH RePORTER |
What this research studies
This research investigates how lowering blood pressure and using specific medications affect kidney function in patients with chronic kidney disease (CKD). It aims to determine the extent of acute declines in kidney function that occur during these treatments and whether these changes could lead to long-term health risks. By analyzing patient data, the study seeks to identify safe thresholds for blood pressure management and medication use, ultimately improving treatment strategies for CKD patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with chronic kidney disease who are undergoing treatment for high blood pressure.
Not a fit: Patients without chronic kidney disease or those not experiencing high blood pressure may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer and more effective blood pressure management strategies for patients with chronic kidney disease.
How similar studies have performed: Previous research has shown that managing blood pressure and using renin-angiotensin system blockers can improve outcomes in CKD, but this specific investigation into acute declines in kidney function is relatively novel.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Ku, Elaine — University of California, San Francisco
- Study coordinator: Ku, Elaine
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.