Understanding Kidney Cells for Better Health

PREcision Medicine through IntErrogation of Rna in the kidnEy (PREMIERE)

['FUNDING_U01'] · UNIVERSITY OF MICHIGAN AT ANN ARBOR · NIH-11174464

This project aims to understand how individual kidney cells work in healthy and diseased kidneys to help develop new, targeted treatments.

Quick facts

Phase['FUNDING_U01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF MICHIGAN AT ANN ARBOR (nih funded)
Locations1 site (ANN ARBOR, UNITED STATES)
Trial IDNIH-11174464 on ClinicalTrials.gov

What this research studies

Your kidneys are vital for filtering waste, balancing fluids, and controlling blood pressure. To create better treatments for kidney diseases, we need to understand exactly how different kidney cells function and change when you're sick. This project uses advanced techniques to look closely at individual cells from kidney samples, linking these cell changes to specific kidney conditions. By doing this, we hope to discover new ways to treat kidney disease more effectively.

Who could benefit from this research

Good fit: Patients with kidney disease who may undergo kidney biopsies as part of their care could potentially contribute to or benefit from this type of research.

Not a fit: Patients without kidney disease or those not undergoing kidney biopsies would not directly benefit from this specific research.

Why it matters

Potential benefit: If successful, this work could lead to the development of new, more precise treatments for various kidney diseases.

How similar studies have performed: Previous extensive studies by this and other groups have already identified molecular disease mechanisms and helped develop new markers and therapies.

Where this research is happening

ANN ARBOR, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.