Understanding Jumping Genes in Health and Disease
Understanding the regulation and impact of transposable elements in Vertebrate health and disease
['FUNDING_OTHER'] · UNIVERSITY OF SOUTHERN CALIFORNIA · NIH-11098664
This research explores how certain "jumping genes" in our bodies are controlled and how they affect our health throughout life, especially in conditions like cancer.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF SOUTHERN CALIFORNIA (nih funded) |
| Locations | 1 site (Los Angeles, UNITED STATES) |
| Trial ID | NIH-11098664 on ClinicalTrials.gov |
What this research studies
Our bodies have many different cell types, each with unique ways of controlling their genes, which is vital for development and staying healthy as adults. When this control goes wrong, it can lead to diseases like cancer and age-related decline. This project focuses on "jumping genes," which are often overlooked but make up a large part of our genetic material. We want to learn how these genes are regulated in healthy tissues and how their activity might differ between males and females, as well as how they contribute to overall health.
Who could benefit from this research
Good fit: This foundational research aims to benefit anyone affected by diseases like cancer or age-related health issues, particularly adults over 21, including those of African descent.
Not a fit: Patients seeking immediate new treatments or direct clinical interventions will not find them through this basic science project.
Why it matters
Potential benefit: By uncovering how these "jumping genes" work, this research could lead to new ways to understand, prevent, or treat diseases like cancer and conditions related to aging.
How similar studies have performed: This project explores understudied mechanisms of genomic regulation, building on emerging evidence that suggests a significant role for these elements in health and disease.
Where this research is happening
Los Angeles, UNITED STATES
- UNIVERSITY OF SOUTHERN CALIFORNIA — Los Angeles, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BENAYOUN, BERENICE ANATH — UNIVERSITY OF SOUTHERN CALIFORNIA
- Study coordinator: BENAYOUN, BERENICE ANATH
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers