Understanding injury in preterm infants with low oxygen levels

Who could benefit from this research

What this research studies

This research focuses on preterm infants who experience intermittent hypoxemia, which are episodes of low blood oxygen levels. The principal investigator, Dr. Elie Abu Jawdeh, aims to learn more about the biological mechanisms that lead to injury in these infants and to identify potential biomarkers that could help in diagnosing and treating these conditions. The research involves a combination of hands-on laboratory work, mentorship, and formal education to develop new treatments for the complications associated with prematurity. By understanding these mechanisms, the research hopes to improve outcomes for vulnerable preterm infants.

Why it matters

Where this research is happening

• Ut Southwestern Medical Center
  Dallas, United States Active

Researchers

• Principal investigator: Abu Jawdeh, Elie G — Ut Southwestern Medical Center
• Study coordinator: Abu Jawdeh, Elie G

Related research

Other NIH-funded projects on the same topics.

• Understanding the long-term effects of breathing issues in preterm infants

  This study is looking at how short episodes of low oxygen levels in preterm babies might impact their health as they grow up, especially concerning breathing problems like asthma and sleep issues, so we can find ways to help those babies early on for a healthier future.

  NIH research Lurie Children's Hospital of Chicago · Chicago, United States · NIH-11004618

• Screening and treatment of Chlamydia infection in pregnancy to help prevent preterm birth

  This grant studies whether screening pregnant people for Chlamydia trachomatis and treating those who are positive can reduce the risk of preterm birth.

  NIH research University of California, San Diego · La Jolla, United States · NIH-11617691

• Preterm infant body composition and early-life health after NICU stay

  This grant studies how body composition in very preterm babies relates to later brain development and risk of obesity or diabetes, with findings meant to improve care from NICU through early childhood.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11600939

• Brain injury risk in preterm babies with heart disease and how surgery choices affect their brains

  This project follows newborns with congenital heart disease born early to understand how their brains are affected and how different surgical approaches might influence outcomes.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11520488

• Xylitol to Prevent Periodontal Disease and Preterm Birth in Pregnancy and Early Childhood

  A safe, inexpensive chewable gum approach using xylitol is tested to help pregnant people reduce gum disease and lower the chance of preterm birth and related child health problems.

  NIH research University of Washington · Seattle, United States · NIH-11478593

• Screening and treatment for Chlamydia infection to help prevent preterm birth

  A study in pregnant people will test whether screening for Chlamydia trachomatis and treating it during pregnancy can reduce the risk of babies being born too early.

  NIH research University of California, San Diego · La Jolla, United States · NIH-11474446

About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.