Understanding injuries related to neonatal brachial plexus palsy during childbirth
Investigating Injury Tolerance and Mechanisms of Neonatal Brachial Plexus Palsy and Associated Injuries
This study is looking at how certain injuries during childbirth can affect babies' arms and aims to find ways to spot these issues early and improve care for infants who might be at risk.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Temple Univ of the Commonwealth NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-11059059 on NIH RePORTER |
What this research studies
This research investigates neonatal brachial plexus palsy (NBPP), a complication that can occur during childbirth, leading to significant long-term effects. The study uses a unique neonatal piglet model to explore the strains and forces on the brachial plexus that may cause spinal cord injuries. It aims to identify systemic biomarkers for early diagnosis and develop computational models to predict risks associated with complicated deliveries. By understanding these mechanisms, the research seeks to inform prevention and treatment strategies for affected infants.
Who could benefit from this research
Good fit: Ideal candidates for this research are newborns who experience complications during childbirth, particularly those at risk for brachial plexus injuries.
Not a fit: Patients who are not newborns or those who do not have a history of childbirth complications may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools and preventive measures for neonatal brachial plexus palsy, ultimately enhancing outcomes for affected infants.
How similar studies have performed: While the specific approach of using a neonatal piglet model is innovative, previous research has shown promise in understanding similar injury mechanisms in other contexts.
Where this research is happening
Philadelphia, United States
- Temple Univ of the Commonwealth — Philadelphia, United States (Active)
Researchers
- Principal investigator: Singh, Anita — Temple Univ of the Commonwealth
- Study coordinator: Singh, Anita
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.