Understanding inflammation's role in heart and diabetes risks for Latinos
Inflammatory mediators of cardiometabolic risk in Latinos
This study is looking at how ongoing low-level inflammation affects heart and diabetes risks in Latino communities, with the goal of finding new ways to prevent and treat these issues by focusing on certain substances in the body.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project ID | NIH-10558470 on NIH RePORTER |
What this research studies
This research investigates how chronic low-grade inflammation contributes to cardiometabolic risks and type 2 diabetes (T2D) specifically in Latino populations. By identifying specific inflammatory mediators, the study aims to uncover new targets for prevention and treatment of these conditions. The approach includes analyzing lipid mediators known as eicosanoids, which have not been thoroughly studied in relation to these health issues. This research seeks to provide insights that could lead to tailored therapies for those at highest risk.
Who could benefit from this research
Good fit: Ideal candidates for this research are Latino individuals aged 21 and older who are at risk for or have been diagnosed with type 2 diabetes or related cardiovascular conditions.
Not a fit: Patients who are not Latino or those under 21 years of age may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for type 2 diabetes and cardiovascular diseases in Latino populations.
How similar studies have performed: While some studies have explored eicosanoids in relation to cardiometabolic risks, this research aims to fill a significant gap by examining a broader range of mediators in a specific population, making it a novel approach.
Where this research is happening
Chapel Hill, United States
- Univ of North Carolina Chapel Hill — Chapel Hill, United States (Active)
Researchers
- Principal investigator: Avery, Christy Leigh — Univ of North Carolina Chapel Hill
- Study coordinator: Avery, Christy Leigh
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.