Understanding inflammation and its effects on health
Official title: BioSystems Networks and Translational Research - Insights into Inflammation (BioSNTR-II)
Funded at South Dakota State University · NIH-11035153 · Data updated 2026-11-12
This study is looking at how inflammation works in the body, especially how certain immune cells talk to each other, and it aims to find new ways to help people with inflammatory conditions feel better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | South Dakota State University NIH-funded |
| Lab location | 1 site (Brookings, United States) |
| Project start | March 20, 2022 |
| Project end | January 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $1,966,320 |
| NIH project number | 5P20GM135008-04 |
| Project ID | NIH-11035153 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are individuals suffering from chronic inflammatory conditions or related diseases.
✕Less likely to help
Patients with acute inflammatory responses that do not require long-term management may not benefit from this research.
What this research studies
This research focuses on the mechanisms of inflammation at the molecular, cellular, and tissue levels. It employs a multidisciplinary approach to explore how cells communicate during inflammation, particularly looking at macrophages and lymphatic systems. The project includes advanced techniques like transcriptome sequencing and CRISPR gene editing to investigate these processes. Patients may benefit from insights that could lead to new treatments for inflammatory conditions.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for various inflammatory diseases.
How similar studies have gone: Previous research has shown promise in understanding inflammation through similar multidisciplinary approaches, indicating potential for success.
Where this research is happening
-
South Dakota State University
Brookings, United States Active
Researchers
- Principal investigator: Hoppe, Adam David — South Dakota State University
- Study coordinator: Hoppe, Adam David
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.