Understanding infections in diabetic foot ulcers and their recurrence
Diabetic Foot Ulcer Biofilm Infection and Recurrence
This study is looking at how infections in diabetic foot ulcers can come back and cause serious problems, like amputations, and it aims to find better ways to detect and treat these infections for people with diabetes.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project ID | NIH-10854979 on NIH RePORTER |
What this research studies
This research investigates the role of biofilm infections in diabetic foot ulcers (DFUs), which are a significant complication for individuals with diabetes. The study aims to understand how these infections can lead to the recurrence of DFUs, which often result in severe outcomes such as amputations. By examining the behavior of bacteria in biofilm form, the research seeks to improve detection methods and treatment strategies for DFUs. The work is being conducted at two major centers, Indiana University and Stanford University, to gather comprehensive data.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with type 2 diabetes who have experienced diabetic foot ulcers.
Not a fit: Patients without diabetes or those who have not experienced diabetic foot ulcers may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better prevention and treatment strategies for diabetic foot ulcers, potentially reducing the rates of recurrence and amputations.
How similar studies have performed: Previous research has shown that addressing biofilm infections can improve outcomes in chronic wound care, suggesting a promising avenue for this investigation.
Where this research is happening
Pittsburgh, United States
- University of Pittsburgh at Pittsburgh — Pittsburgh, United States (Active)
Researchers
- Principal investigator: Sen, Chandan K — University of Pittsburgh at Pittsburgh
- Study coordinator: Sen, Chandan K
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.