Understanding infections in children with tracheostomies
Official title: Prognostic modeling of pediatric tracheostomy-associated respiratory tract infections
Funded at Johns Hopkins University · NIH-11031347 · Data updated 2026-11-12
This study is looking at what causes respiratory infections in children with tracheostomies, so we can better understand which kids might get sick more often and help them stay healthier.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | March 17, 2023 |
| Project end | February 29, 2028 |
| Funding year | 2025 |
| Award (this year) | $196,887 |
| NIH project number | 5K23HL163331-03 |
| Project ID | NIH-11031347 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children aged 0-11 years who have undergone tracheostomy and are at risk for respiratory infections.
✕Less likely to help
Patients who do not have a tracheostomy or are older than 11 years may not benefit from this research.
What this research studies
This research investigates the factors that contribute to respiratory infections in children who have undergone tracheostomy. By analyzing data from a cohort of affected children, the study aims to identify clinical and immune response factors that lead to recurrent hospitalizations due to infections caused by Pseudomonas aeruginosa. The goal is to develop a prognostic model that can predict which patients are at higher risk for these infections, ultimately improving care and outcomes for these children.
Why it matters
Potential benefit: If successful, this research could lead to better prevention and treatment strategies for respiratory infections in children with tracheostomies.
How similar studies have gone: Previous research has shown promise in identifying risk factors for infections in similar pediatric populations, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Researchers
- Principal investigator: Morrison, John M — Johns Hopkins University
- Study coordinator: Morrison, John M
Related research
Other NIH-funded projects on the same topics.
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Enhanced primary care telemedicine for kids with lung and airway infections
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Novel Tracheostomy Alert Device for Children and Adults
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Understanding how vaccines work in real life against flu and COVID-19
A real-world study at a major university hospital will track how well flu and COVID-19 vaccines protect ambulatory patients who have respiratory infections.
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EPIPHANY: Using AI to guide when to do tracheostomy for patients on long ventilators
An AI-based platform aims to help ICU teams decide the best time for tracheostomy in patients on prolonged mechanical ventilation, potentially reducing complications and costs.
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Airway microbes and viral infections in children with tracheostomies
This project looks at how airway germs and the body's response during viral infections affect illness in children who have tracheostomies and use home ventilation.
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How flu and COVID-19 vaccines protect people seen in outpatient clinics
This project measures how well influenza and COVID-19 vaccines protect people who come to outpatient clinics with respiratory symptoms.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.