Understanding infection risks in young children
Inflammatory subtypes and multi-omic determinants of early life infection risk
['FUNDING_CAREER'] · BRIGHAM AND WOMEN'S HOSPITAL · NIH-10947656
This study is looking at how certain biological factors might make young children more likely to get respiratory infections, and it’s for families with kids under five who want to help us understand how genes and the environment affect their little ones' health.
Quick facts
| Phase | ['FUNDING_CAREER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BRIGHAM AND WOMEN'S HOSPITAL (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-10947656 on ClinicalTrials.gov |
What this research studies
This research investigates the biological factors that contribute to respiratory infection risks in children under five years old. By analyzing data from a cohort of children, the study aims to identify distinct inflammatory profiles that may predict susceptibility to infections. The approach combines advanced techniques in biochemistry and immunology to explore how genetic and environmental factors interact in early life. Participants will be monitored over several years to gather comprehensive data on their health and infection experiences.
Who could benefit from this research
Good fit: Ideal candidates for this research are children under the age of five, particularly those with a history of respiratory infections.
Not a fit: Patients who are older than five years or do not have a history of respiratory infections may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing respiratory infections in young children.
How similar studies have performed: Previous research has shown promise in using multi-omic approaches to understand disease susceptibility, indicating potential for success in this novel investigation.
Where this research is happening
BOSTON, UNITED STATES
- BRIGHAM AND WOMEN'S HOSPITAL — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PRINCE, NICOLE — BRIGHAM AND WOMEN'S HOSPITAL
- Study coordinator: PRINCE, NICOLE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Airway infections