Understanding Individual Brain Changes in Neurocritical Care

SCH: Tracking Individual Brain State Trajectories: Methods and Applications in Precision Neurocritical Care

NIH-funded research Washington University · NIH-11131165

This project aims to better understand how individual brains change after an injury using brain wave recordings to help critically ill patients.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWashington University NIH-funded
Lab location1 site (Saint Louis, United States)
Project IDNIH-11131165 on NIH RePORTER

What this research studies

When someone has a severe brain injury, it's crucial to track their brain activity closely to prevent further damage and improve their recovery. This project uses a new way to look at brain wave data, like from an EEG, to create a personalized picture of how each patient's brain is working. By focusing on individual brain patterns, we hope to overcome challenges with general population data and better predict when secondary injuries, like seizures, might occur. This personalized approach could help doctors make more timely decisions and improve long-term outcomes for patients.

Who could benefit from this research

Good fit: This research is relevant for adult patients, 21 years and older, who have experienced an acquired brain injury and are receiving neurocritical care.

Not a fit: Patients without an acquired brain injury or those not in a neurocritical care setting would not directly benefit from this specific research.

Why it matters

Potential benefit: If successful, this work could lead to new tools that help doctors anticipate and prevent further brain damage in critically ill patients, potentially improving their recovery and reducing long-term problems.

How similar studies have performed: While electrophysiological monitoring is common, this project proposes a novel quantitative framework to model individual brain dynamics, aiming to overcome limitations of current population-level approaches.

Where this research is happening

Saint Louis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired brain injury
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.