Understanding impulsivity in suicidal behavior among adolescents
Official title: Inhibitory Mechanisms of Negative Urgency in Adolescent Suicidal Behavior
Funded at University of Minnesota · NIH-10895481 · Data updated 2026-11-12
This study is looking at how the brain works in teenagers who sometimes act on impulse when feeling really upset, and it aims to find ways to help those aged 12 to 20 who might be at risk of suicide.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project start | August 1, 2023 |
| Project end | July 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $198,180 |
| NIH project number | 5K23MH127307-02 |
| Project ID | NIH-10895481 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adolescents aged 12 to 20 who have experienced suicidal thoughts or behaviors.
✕Less likely to help
Patients outside the age range of 12 to 20 or those without a history of suicidal behavior may not benefit from this research.
What this research studies
This research investigates the brain mechanisms behind impulsivity in adolescents who exhibit suicidal behavior. It focuses on understanding how negative emotions can lead to rash actions, particularly in young individuals aged 12 to 20. Using advanced techniques like transcranial magnetic stimulation (TMS), the study aims to explore how certain brain areas, particularly the dorsolateral prefrontal cortex, function in these situations. The findings could help develop targeted interventions for adolescents at risk of suicide.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments and interventions for adolescents struggling with suicidal thoughts and behaviors.
How similar studies have gone: Previous research has shown promise in understanding impulsivity and its neural correlates, suggesting that this approach could yield valuable insights.
Where this research is happening
-
University of Minnesota
Minneapolis, United States Active
Researchers
- Principal investigator: Lewis, Charles P. — University of Minnesota
- Study coordinator: Lewis, Charles P.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.