Understanding Immunity and Viruses in Asthma
Official title: Innate Immunity and Viral Infection in Asthma
Funded at University of Arizona · NIH-11132917 · Data updated 2026-11-12
This project explores how our body's natural defenses respond to common viruses in people with asthma.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Arizona NIH-funded |
| Lab location | 1 site (Tucson, United States) |
| Project start | June 1, 2016 |
| Project end | May 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $1,431,641 |
| NIH project number | 5U19AI125357-10 |
| Project ID | NIH-11132917 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients with asthma who experience viral infections, including those with rhinovirus C, influenza A, or SARS-CoV-2, are the focus of this research.
✕Less likely to help
Patients without asthma or those whose conditions are not related to viral infections may not directly benefit from this specific research.
What this research studies
This research focuses on specific immune factors, such as certain phospholipids and proteins, to understand their role in how the body fights off viral infections in individuals with asthma. We are looking at how these factors influence the body's response to viruses like rhinovirus C, influenza A, and SARS-CoV-2. The goal is to discover if these natural immune components can help protect against severe illness or even offer some benefits when asthma is present. By uncovering how these parts of our immune system work together, we hope to find new ways to help people with asthma manage viral infections.
Why it matters
Potential benefit: This work could lead to new strategies for protecting people with asthma from severe viral infections and their complications.
How similar studies have gone: The grant mentions innovative preliminary data indicating protective effects of the studied immune factors against viral infections, suggesting some prior success in related areas.
Where this research is happening
-
University of Arizona
Tucson, United States Active
Researchers
- Principal investigator: Kraft, Monica — University of Arizona
- Study coordinator: Kraft, Monica
Related research
Other NIH-funded projects on the same topics.
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-
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This grant studies how group 2 innate lymphoid cells influence asthma in adults to help identify new ways to manage airway inflammation.
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This program will try several approaches — from giving helpful bacteria to babies to allergy immunotherapy and advanced airway testing — to prevent and better treat asthma in children who live in cities.
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IDEAL project helps predict vaccine response, infections, and asthma in early childhood
A Child-focused program will collect and share saliva, blood, and tissue samples from diverse infants to find biological patterns that predict how vaccines work, how respiratory infections occur, and who develops asthma.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.