Understanding immune system changes during pregnancy
MOMI Data Management
This study is looking at how a pregnant person's immune system changes to protect both them and their baby, and it aims to find ways to improve health during pregnancy and help with issues like infertility.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts Institute of Technology NIH-funded |
| Lab location | 1 site (Cambridge, United States) |
| Project ID | NIH-11058451 on NIH RePORTER |
What this research studies
This research investigates how the immune system adapts during pregnancy, shifting from an inflammatory state to an anti-inflammatory one to support fetal development. By analyzing complex biological data, the study aims to identify an 'immunological clock' that regulates these changes throughout gestation. Researchers will collect and integrate data across various biological levels, using vaccines to observe how the immune system responds in real-time. The goal is to enhance maternal health, develop new treatments for infertility, and improve neonatal outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research include pregnant individuals or those experiencing infertility issues.
Not a fit: Patients who are not pregnant or do not have fertility concerns may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for managing pregnancy-related health issues and infertility.
How similar studies have performed: Other research has shown promise in understanding immune system dynamics during pregnancy, suggesting that this approach could yield valuable insights.
Where this research is happening
Cambridge, United States
- Massachusetts Institute of Technology — Cambridge, United States (Active)
Researchers
- Principal investigator: Lauffenburger, Douglas a — Massachusetts Institute of Technology
- Study coordinator: Lauffenburger, Douglas a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.