Understanding immune responses to viruses and their protection mechanisms
Official title: Core E: Immunogenicity and Immune Correlates Core
Funded at Washington University · NIH-10863696 · Data updated 2026-11-12
This study is looking at how our immune systems respond to different viruses in people and animals, using tests to see how well our bodies fight off infections, and it aims to find patterns that could help create better vaccines for new viruses that might cause pandemics.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project start | September 11, 2024 |
| Project end | August 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $5,024,019 |
| NIH project number | 1U19AI181984-01 |
| Project ID | NIH-10863696 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals who are at risk of viral infections or those who may benefit from enhanced vaccine strategies.
✕Less likely to help
Patients who are not at risk for viral infections or those who have already been vaccinated against the specific viruses being studied may not receive benefit from this research.
What this research studies
This research focuses on measuring immune responses to various viruses in both humans and animals. By conducting a series of assays, the team aims to quantify how the immune system reacts, particularly looking at antibodies and cellular responses. The project will also utilize machine learning to identify patterns that could indicate how well the immune system can protect against these viruses. Ultimately, the goal is to establish immune correlates that could help in developing vaccines for emerging viruses with pandemic potential.
Why it matters
Potential benefit: If successful, this research could lead to improved vaccine development and better protection against viral infections.
How similar studies have gone: Previous research has shown success in identifying immune correlates for other viral infections, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Washington University
Saint Louis, United States Active
Researchers
- Principal investigator: Mcelroy, Anita K — Washington University
- Study coordinator: Mcelroy, Anita K
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.