Understanding immune responses to SARS-CoV-2

Johns Hopkins Excellence in Pathogenesis and Immunity Center for SARS-CoV-2 (JH-EPICS)

['FUNDING_OTHER'] · JOHNS HOPKINS UNIVERSITY · NIH-11159235

This study is looking at how our immune system fights the COVID-19 virus to find out what helps protect us and what might cause more severe illness, by examining blood samples from patients over time.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorJOHNS HOPKINS UNIVERSITY (nih funded)
Locations1 site (BALTIMORE, UNITED STATES)
Trial IDNIH-11159235 on ClinicalTrials.gov

What this research studies

This research focuses on the immune responses to the SARS-CoV-2 virus, which causes COVID-19. It aims to identify which immune responses protect against the virus and which may lead to severe disease. The study involves analyzing blood samples from COVID-19 patients over time to evaluate different immune components, including antibodies and T cells. By using advanced techniques like flow cytometry, researchers will explore how the immune system reacts to the virus and how this knowledge can inform treatment strategies.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals who have tested positive for COVID-19 and are willing to provide blood samples for analysis.

Not a fit: Patients who have not been infected with COVID-19 or those who are not willing to participate in blood sample collection may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding of COVID-19 immunity and better treatment options for patients.

How similar studies have performed: Other research has shown success in understanding immune responses to viral infections, making this approach promising for COVID-19.

Where this research is happening

BALTIMORE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: COVID disease severity

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.