Understanding immune responses to SARS-CoV-2

Johns Hopkins Excellence in Pathogenesis and Immunity Center for SARS-CoV-2 (JH-EPICS)

NIH-funded research Johns Hopkins University · NIH-10855020

This study is looking at how your immune system responds to the COVID-19 virus to understand what helps protect you from getting sick and what might cause complications, by examining blood samples from COVID-19 patients over time.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionJohns Hopkins University NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-10855020 on NIH RePORTER

What this research studies

This research focuses on the immune responses to the SARS-CoV-2 virus, which causes COVID-19. It aims to identify the differences between immune responses that protect against the virus and those that may lead to disease complications. The study involves analyzing blood samples from COVID-19 patients over time to evaluate various immune cells and antibodies. By using advanced techniques like flow cytometry, researchers will explore how different immune components interact during infection.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals who have been diagnosed with COVID-19 and are willing to provide blood samples for analysis.

Not a fit: Patients who have not been infected with SARS-CoV-2 or those with other unrelated health conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatments and vaccines for COVID-19 by enhancing our understanding of immune protection.

How similar studies have performed: Other research has shown success in understanding immune responses to viral infections, making this approach promising yet still innovative in the context of SARS-CoV-2.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.