Understanding immune responses to respiratory viral infections in vulnerable populations
Systems Immunology profiling of respiratory viral infections in vulnerable populations
This study is looking at how common respiratory viruses impact children and adults with conditions like asthma and rheumatoid arthritis, to better understand their immune responses and find new treatments for those who might get sicker from these infections.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Benaroya Research Inst at Virginia Mason NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-11043337 on NIH RePORTER |
What this research studies
This research investigates how acute respiratory viral infections (ARVI) affect vulnerable groups, particularly children and adults with chronic conditions like asthma and rheumatoid arthritis. By analyzing immune responses at the molecular and cellular levels, the study aims to identify why these populations experience more severe infections and how their immune systems react. The research includes detailed assessments of immune responses in both pediatric and adult subjects, focusing on factors like asthma, allergies, and obesity. The ultimate goal is to discover new therapies and identify individuals at higher risk for complications from ARVI.
Who could benefit from this research
Good fit: Ideal candidates include children with asthma or allergies and adults with rheumatoid arthritis or other chronic inflammatory diseases.
Not a fit: Patients without chronic respiratory conditions or those not in the vulnerable age groups may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments and preventive strategies for respiratory viral infections in vulnerable populations.
How similar studies have performed: Previous research has shown promising results in understanding immune responses to respiratory infections, making this approach both relevant and potentially impactful.
Where this research is happening
Seattle, United States
- Benaroya Research Inst at Virginia Mason — Seattle, United States (Active)
Researchers
- Principal investigator: Mikacenic, Carmen R — Benaroya Research Inst at Virginia Mason
- Study coordinator: Mikacenic, Carmen R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.