Understanding immune responses to COVID-19 vaccines in Latino patients
SARS-CoV-2 correlates of protection in a Latino-origin population
['FUNDING_U01'] · UNIVERSITY OF PUERTO RICO MED SCIENCES · NIH-10706728
This study is looking at how well COVID-19 mRNA vaccines work for Latino patients who have had stem cell transplants, focusing on how their immune systems respond to the vaccine, so we can better support their health during the pandemic.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF PUERTO RICO MED SCIENCES (nih funded) |
| Locations | 1 site (SAN JUAN, UNITED STATES) |
| Trial ID | NIH-10706728 on ClinicalTrials.gov |
What this research studies
This research investigates how Latino-origin patients, particularly those who have undergone hematopoietic stem cell transplants, respond to COVID-19 mRNA vaccines. It aims to identify the immune responses generated by these vaccines, including the roles of T and B cells in fighting off the virus. By monitoring both asymptomatic and symptomatic infections, the study seeks to understand the effectiveness of the vaccine in this vulnerable population. The findings could help improve vaccination strategies and patient care during the ongoing pandemic.
Who could benefit from this research
Good fit: Ideal candidates for this research are Latino individuals who have received hematopoietic stem cell transplants.
Not a fit: Patients who are not of Latino origin or who have not undergone hematopoietic stem cell transplants may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance vaccine efficacy and safety for Latino patients with compromised immune systems.
How similar studies have performed: Other research has shown promising results in understanding vaccine responses in immunocompromised populations, making this approach both relevant and necessary.
Where this research is happening
SAN JUAN, UNITED STATES
- UNIVERSITY OF PUERTO RICO MED SCIENCES — SAN JUAN, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SARIOL, CARLOS A — UNIVERSITY OF PUERTO RICO MED SCIENCES
- Study coordinator: SARIOL, CARLOS A
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.