Understanding immune responses in people living with HIV and cardiovascular disease
Immunophenotyping for precision medicine for cardiovascular disease in people living with HIV
['FUNDING_R01'] · ALBERT EINSTEIN COLLEGE OF MEDICINE · NIH-10453453
This study is looking at how changes in immune cells might affect the risk of heart disease in people living with HIV, and it aims to find ways to better manage heart health for this group.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ALBERT EINSTEIN COLLEGE OF MEDICINE (nih funded) |
| Locations | 1 site (BRONX, UNITED STATES) |
| Trial ID | NIH-10453453 on ClinicalTrials.gov |
What this research studies
This research investigates how immune cell changes in people living with HIV relate to the risk of developing cardiovascular disease (CVD). By studying a diverse group of participants, including both men and women, the research aims to identify specific immune cell types and gene expressions that contribute to CVD in this population. Advanced techniques like single-cell RNA sequencing will be used to analyze blood samples, helping to uncover the complex interactions between HIV, inflammation, and cardiovascular health. The goal is to improve precision medicine approaches for managing CVD in individuals with HIV.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV, particularly those who are older or at risk for cardiovascular disease.
Not a fit: Patients who are not living with HIV or who do not have cardiovascular disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized treatment strategies for preventing cardiovascular disease in people living with HIV.
How similar studies have performed: Previous research has shown promising results in understanding immune responses related to cardiovascular disease in other populations, suggesting that this approach may yield valuable insights.
Where this research is happening
BRONX, UNITED STATES
- ALBERT EINSTEIN COLLEGE OF MEDICINE — BRONX, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KAPLAN, ROBERT C — ALBERT EINSTEIN COLLEGE OF MEDICINE
- Study coordinator: KAPLAN, ROBERT C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.