Understanding immune responses in patients with chronic critical illness after severe trauma or sepsis
Immunological Endotyping of Chronic Critical Illness after Severe Trauma or Sepsis
This study is looking at how the immune system works in people who have survived serious injuries or infections and are dealing with ongoing health problems, like frequent infections and muscle weakness, to find better ways to help them feel better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-10892795 on NIH RePORTER |
What this research studies
This research investigates how the immune system behaves in patients who have survived severe trauma or sepsis and are experiencing chronic critical illness. It focuses on identifying specific immune responses and patterns that contribute to ongoing health issues, such as recurrent infections and muscle weakness. By analyzing the immune profiles of these patients, the study aims to uncover the underlying mechanisms of their condition and improve treatment strategies. Patients may undergo assessments and provide samples to help researchers understand the relationship between their immune response and chronic illness.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients who have survived severe trauma or sepsis and are currently experiencing chronic critical illness.
Not a fit: Patients who have not experienced severe trauma or sepsis, or who do not have chronic critical illness, may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments and better outcomes for patients suffering from chronic critical illness following severe trauma or sepsis.
How similar studies have performed: Previous research has shown promise in understanding immune responses in critically ill patients, suggesting that this approach could yield valuable insights.
Where this research is happening
Seattle, United States
- University of Washington — Seattle, United States (Active)
Researchers
- Principal investigator: Brakenridge, Scott Charles — University of Washington
- Study coordinator: Brakenridge, Scott Charles
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.