Understanding immune responses in organ and tissue transplantation
IMMUNE EPITOPE AND ANALYSIS PROGRAM: Transplantation of organs, tissues and cells
This study is looking at how our immune system interacts with transplanted organs to help improve the chances of a successful transplant for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | La Jolla Institute for Immunology NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-11041927 on NIH RePORTER |
What this research studies
This research focuses on the Immune Epitope Database and Analysis Program, which compiles detailed information about antibodies and T cell epitopes relevant to organ and tissue transplantation. It utilizes extensive literature and data from various contractors to predict and visualize how these immune components interact with transplanted organs. By analyzing over 20,500 curated references, the program aims to enhance our understanding of immune responses that can affect transplant success and patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who are undergoing or have undergone organ or tissue transplantation.
Not a fit: Patients who are not candidates for transplantation or those with conditions unrelated to immune responses in transplantation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for organ and tissue transplantation, potentially increasing transplant success rates and patient survival.
How similar studies have performed: Previous research has shown success in utilizing epitope mapping and immune analysis to improve transplantation outcomes, indicating that this approach has a solid foundation.
Where this research is happening
La Jolla, United States
- La Jolla Institute for Immunology — La Jolla, United States (Active)
Researchers
- Principal investigator: Wilson, Stephen — La Jolla Institute for Immunology
- Study coordinator: Wilson, Stephen
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.