Understanding immune responses in organ and tissue transplantation
IMMUNE EPITOPE AND ANALYSIS PROGRAM: Transplantation of organs, tissues and cells
This study is looking at how certain immune proteins interact with transplanted organs to help doctors match donors and recipients better, which could lead to more successful transplants for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | La Jolla Institute for Immunology NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-10788231 on NIH RePORTER |
What this research studies
This research focuses on the Immune Epitope Database and Analysis Program, which compiles detailed information about antibodies and T cell epitopes relevant to organ and tissue transplantation. It utilizes extensive literature and data from epitope discovery to predict and visualize how these immune components interact with transplanted organs. Patients can benefit from improved matching and understanding of immune responses, potentially leading to better transplant outcomes.
Who could benefit from this research
Good fit: Ideal candidates include individuals awaiting organ or tissue transplants who may benefit from tailored immunological assessments.
Not a fit: Patients who are not candidates for organ or tissue transplantation will likely not benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance the success rates of organ and tissue transplants by improving immune compatibility.
How similar studies have performed: Previous research has shown success in using epitope mapping to improve transplant outcomes, indicating that this approach is promising.
Where this research is happening
La Jolla, United States
- La Jolla Institute for Immunology — La Jolla, United States (Active)
Researchers
- Principal investigator: Wilson, Stephen — La Jolla Institute for Immunology
- Study coordinator: Wilson, Stephen
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.