Understanding immune responses in organ and tissue transplantation
IMMUNE EPITOPE AND ANALYSIS PROGRAM: Transplantation of organs, tissues and cells
This study is all about helping people who need organ transplants by learning more about how our immune system reacts to new tissues, so we can make transplants work better and more successfully.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | La Jolla Institute for Immunology NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-10551168 on NIH RePORTER |
What this research studies
This research focuses on the Immune Epitope Database and Analysis Program, which compiles detailed information about antibodies and T cell epitopes relevant to organ and tissue transplantation. It utilizes extensive literature and data from epitope discovery to create predictive tools for understanding immune responses. Patients can benefit from this research as it aims to improve the success rates of organ transplants by better understanding how the immune system interacts with transplanted tissues.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who are undergoing or considering organ or tissue transplantation.
Not a fit: Patients who are not candidates for organ transplantation or those with conditions unrelated to immune responses in transplantation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved outcomes for patients receiving organ transplants by enhancing our understanding of immune responses.
How similar studies have performed: Previous research has shown success in utilizing epitope mapping and immune analysis to improve transplant outcomes, indicating that this approach is promising.
Where this research is happening
La Jolla, United States
- La Jolla Institute for Immunology — La Jolla, United States (Active)
Researchers
- Principal investigator: Wilson, Stephen — La Jolla Institute for Immunology
- Study coordinator: Wilson, Stephen
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.