Understanding immune responses in organ and tissue transplantation
IMMUNE EPITOPE AND ANALYSIS PROGRAM: Transplantation of organs, tissues and cells
['FUNDING_OTHER'] · LA JOLLA INSTITUTE FOR IMMUNOLOGY · NIH-10021129
This study is looking at how our immune system interacts with transplanted organs to help doctors better match donors and recipients, which could lead to better outcomes for patients receiving organ transplants.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | LA JOLLA INSTITUTE FOR IMMUNOLOGY (nih funded) |
| Locations | 1 site (LA JOLLA, UNITED STATES) |
| Trial ID | NIH-10021129 on ClinicalTrials.gov |
What this research studies
This research focuses on the Immune Epitope Database and Analysis Program, which compiles detailed information about antibodies and T cell epitopes relevant to organ and tissue transplantation. It utilizes extensive literature and data from epitope discovery to predict and visualize how these immune components interact with transplanted organs. Patients may benefit from improved matching and outcomes in organ transplants through enhanced understanding of immune responses.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals awaiting organ transplants or those who have received transplants and are experiencing complications.
Not a fit: Patients who are not candidates for organ transplantation or those with unrelated medical conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better matching of organ donors and recipients, improving transplant success rates.
How similar studies have performed: Previous research has shown success in utilizing epitope mapping to improve transplant outcomes, indicating a promising approach.
Where this research is happening
LA JOLLA, UNITED STATES
- LA JOLLA INSTITUTE FOR IMMUNOLOGY — LA JOLLA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SETTE, ALESSANDRO — LA JOLLA INSTITUTE FOR IMMUNOLOGY
- Study coordinator: SETTE, ALESSANDRO
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.