Understanding immune responses in liver transplant rejection
Immunologic Biomarkers of Rejection in Clinical Liver Transplantation
This study is looking at how the immune system responds to liver transplants to find signs that might show if the body is rejecting the new liver, and it’s for patients who have had a liver transplant and can help by giving blood samples.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Southern California NIH-funded |
| Lab location | 1 site (Los Angeles, UNITED STATES) |
| Project ID | NIH-10875391 on NIH RePORTER |
What this research studies
This research investigates how the immune system reacts to liver transplants, focusing on identifying specific biomarkers that indicate rejection. Using advanced techniques like mass cytometry, the study aims to analyze immune responses in patients who have undergone liver transplantation. By understanding these mechanisms, the research seeks to develop new diagnostic tools and therapies to improve outcomes for transplant recipients. Patients may be involved in providing blood samples to help characterize these immune responses.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have received a liver transplant and are experiencing or at risk of transplant rejection.
Not a fit: Patients who have not undergone liver transplantation or those with other unrelated medical conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic and treatment options for patients undergoing liver transplantation, ultimately improving their post-transplant health.
How similar studies have performed: Previous research has shown promise in using similar immunological approaches to understand transplant rejection, indicating that this methodology has potential for success.
Where this research is happening
Los Angeles, UNITED STATES
- University of Southern California — Los Angeles, United States (Active)
Researchers
- Principal investigator: Emamaullee, Juliet — University of Southern California
- Study coordinator: Emamaullee, Juliet
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.