Understanding immune responses and outcomes in acute pancreatitis
Immune Signatures and Clinical Outcomes in Acute Pancreatitis
['FUNDING_R01'] · OHIO STATE UNIVERSITY · NIH-11083575
This study is looking at how certain markers in the blood can help doctors predict which patients with acute pancreatitis might have a more severe illness, so they can provide better early treatment.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | OHIO STATE UNIVERSITY (nih funded) |
| Locations | 1 site (Columbus, UNITED STATES) |
| Trial ID | NIH-11083575 on ClinicalTrials.gov |
What this research studies
This research investigates how immune signatures can predict clinical outcomes in patients with acute pancreatitis (AP). By analyzing blood samples from patients, the study aims to identify specific cytokine profiles that can indicate which patients are likely to develop severe forms of the disease. The approach involves a multi-center, observational cohort design, allowing for a diverse patient population and robust data collection. The ultimate goal is to improve early prediction and treatment strategies for patients suffering from acute pancreatitis.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals admitted to the hospital with acute pancreatitis, particularly those at risk of developing severe disease.
Not a fit: Patients with mild acute pancreatitis who are not at risk for severe complications may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better prediction tools and targeted therapies for patients with acute pancreatitis, potentially reducing hospital stays and improving survival rates.
How similar studies have performed: Previous research has shown promise in using immune signatures for predicting outcomes in other conditions, suggesting that this approach may also be effective in acute pancreatitis.
Where this research is happening
Columbus, UNITED STATES
- OHIO STATE UNIVERSITY — Columbus, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PAPACHRISTOU, GEORGIOS I — OHIO STATE UNIVERSITY
- Study coordinator: PAPACHRISTOU, GEORGIOS I
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.