Understanding immune changes in organ transplantation
Mechanistic and Bioinformatics Core
['FUNDING_P01'] · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · NIH-11064092
This study is looking at how our immune system can be trained to better handle organ transplants, and it's for patients who want to learn more about how to improve their treatment and outcomes after receiving a transplant.
Quick facts
| Phase | ['FUNDING_P01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-11064092 on ClinicalTrials.gov |
What this research studies
This research focuses on trained immunity, which involves significant changes in immune cell behavior and gene expression related to organ transplantation. The team at Mount Sinai, led by Dr. Jordi Ochando, will conduct in-depth studies to profile immune cells and validate potential therapeutic targets. They will also manage data and bioinformatics analyses to ensure accurate implementation of their findings. Patients may benefit from improved understanding and treatment strategies related to immune responses in transplantation.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals undergoing or considering organ transplantation.
Not a fit: Patients who are not candidates for organ transplantation or those with unrelated immune disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better management of immune responses in organ transplant patients, potentially improving transplant outcomes.
How similar studies have performed: Previous research on trained immunity has shown promise in improving transplant outcomes, indicating that this approach may be effective.
Where this research is happening
NEW YORK, UNITED STATES
- ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: OCHANDO, JORDI — ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
- Study coordinator: OCHANDO, JORDI
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.