Understanding Immune Cells in Wound Healing
Neutrophil heterogeneity and plasticity in wound healing
This project aims to learn how important immune cells called neutrophils change and work in people recovering from burn injuries.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin-Madison NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project ID | NIH-11121957 on NIH RePORTER |
What this research studies
When you get a burn, your body sends special immune cells called neutrophils to the injury site to help. We want to understand how these cells change over time during the healing process and what factors influence their behavior. By looking closely at these cells, especially those in the blood, we hope to find clues that could predict how a burn injury will heal and if complications might arise. This knowledge could eventually lead to better ways to care for severe burn patients.
Who could benefit from this research
Good fit: Patients who have experienced severe burn injuries might eventually benefit from the insights gained from this fundamental research.
Not a fit: Patients with minor injuries or those whose conditions are unrelated to immune cell function in wound healing may not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to new ways to predict burn complications and improve healing for patients with severe burn injuries.
How similar studies have performed: While there is emerging evidence about neutrophil responses, this specific focus on their changing landscape and plasticity in burn wound healing is a novel area of exploration.
Where this research is happening
Madison, United States
- University of Wisconsin-Madison — Madison, United States (Active)
Researchers
- Principal investigator: Dinh, Huy Quang — University of Wisconsin-Madison
- Study coordinator: Dinh, Huy Quang
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.