Understanding immune cells in sarcoidosis
Multi-Omic Characterization of Immune Cells in Sarcoidosis
['FUNDING_R21'] · OKLAHOMA MEDICAL RESEARCH FOUNDATION · NIH-10954075
This study is looking at how the immune system works in people with sarcoidosis to find helpful clues for diagnosing and tracking the disease, especially focusing on those of African ancestry.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | OKLAHOMA MEDICAL RESEARCH FOUNDATION (nih funded) |
| Locations | 1 site (OKLAHOMA CITY, UNITED STATES) |
| Trial ID | NIH-10954075 on ClinicalTrials.gov |
What this research studies
This research investigates the complex immune responses in patients with sarcoidosis, a disease characterized by the formation of granulomas in various organs. By utilizing advanced techniques in genomics and bioinformatics, the team aims to identify genetic and immune markers that could help in diagnosing and predicting the disease's progression. The study will analyze immune cells from patients to uncover the underlying mechanisms of the disease and how they vary among individuals, particularly those of African ancestry. This multi-omic approach combines data from different biological layers to provide a comprehensive view of the disease.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with sarcoidosis, especially those of African descent.
Not a fit: Patients with sarcoidosis who do not have a genetic or immune component to their disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools and personalized treatment strategies for patients with sarcoidosis.
How similar studies have performed: Previous research has shown promise in using multi-omic approaches to understand complex diseases, indicating potential success for this innovative method.
Where this research is happening
OKLAHOMA CITY, UNITED STATES
- OKLAHOMA MEDICAL RESEARCH FOUNDATION — OKLAHOMA CITY, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MONTGOMERY, COURTNEY — OKLAHOMA MEDICAL RESEARCH FOUNDATION
- Study coordinator: MONTGOMERY, COURTNEY
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Besnier-Boeck Disease, Candidate Disease Gene